Browse all practice questions for the Nightingale Pathophysiology Practice Test. Search by topic, open any question and review its full explanation, then test yourself in the practice quiz.

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  • What has modern imaging technology revealed about osteoarthritis?
  • Hypersplenism occurs when
  • Which disease is defined by malignant plasma cells in the bone marrow?
  • What is the major contributing factor to the development of osteomalacia?
  • Which occurs when normally soluble material such as calcium and oxalate supersaturates the urine and begins the process of crystal formation?
  • Rheumatoid arthritis results from joint inflammation caused by what mechanism?
  • Burkitt lymphoma is a rapidly growing cancer with characteristic involvement of the jaw in the endemic form. Which option lists this correctly?
  • Which outcome is most likely to cause death in pernicious anemia if left untreated?
  • Zollinger-Ellison syndrome is associated with peptic ulcers due to which phenomenon?
  • Postmenopausal osteoporosis occurs largely due to decreased levels of which hormone?
  • Leiomyoma (myomas) are...
  • A patient has a dilated ureter from an obstructed upper urinary tract. Which term describes this condition?
  • Hypoparathyroidism commonly causes which electrolyte disturbance?
  • Fibromyalgia specifically manifests with which symptom?
  • What is the defining pathologic feature common to all forms of leukemia?
  • What is the name for an area where alveoli are ventilated but not perfused?
  • Which condition is described as chest pain due to transient myocardial ischemia without infarction?
  • Which of the following best explains a high V/Q ratio?
  • Which condition is most associated with chest pain due to coronary vasospasm rather than a fixed atherosclerotic lesion?
  • Pernicious anemia can be fatal unless vitamin B12 replacement is given; lifelong replacement is required.
  • A patient with bladder cancer. Which of the following is a typical finding?
  • Which autoimmune disease is mediated by antibodies against the acetylcholine receptor at the neuromuscular junction?
  • What is the classic sign of chronic bronchitis?
  • Lymphoblastic lymphoma is a rare variant of non-Hodgkin lymphoma. From which cell lineage does the vast majority originate?
  • Aortic stenosis results in incomplete emptying of which chamber?
  • Which statement is NOT listed as a contributing factor to constipation?
  • Which disease involves fatigable weakness that improves with rest and is associated with antibodies against the acetylcholine receptor?
  • To which component of the Virchow triad does atherosclerosis correlate?
  • Hereditary hemochromatosis is best described by which statement?
  • Which assessment finding is typical in a patient with multiple myeloma (MM)?
  • What term is used when describing the occurrence of sexual maturation in girls before the age of 6 and in boys before the age of 9?
  • Tissue damage in acute pancreatitis is caused by which mechanism?
  • Which symptom is associated with overactive bladder syndrome?
  • Which is the most common cause of chronic pancreatitis?
  • Benign ovarian cysts are classified as:
  • A patient has non-Hodgkin's lymphoma (NHL). When reviewing the history, which finding is a risk factor for NHL?
  • Dysuria is most closely associated with which bladder condition described in the material?
  • Which condition develops when coronary blood flow or oxygen content is insufficient to meet myocardial metabolic demands?
  • Which assessment finding indicates dyspnea?
  • Parietal (peritoneum) pain is best described as:
  • Which interventions are recommended for a patient with gastroesophageal reflux disease (GERD)?
  • Which complication is a life-threatening concern in rhabdomyolysis?
  • What is the most common cause of portal hypertension?
  • Which statement about lymphomas is accurate?
  • Endometriosis is defined as which?
  • Osteomalacia is best described as which of the following?
  • Which description matches a spermatocele?
  • Which cancer screening test is used for routine screening of cervical cancer?
  • Reflux esophagitis is defined as?
  • Which statement best describes the most common cause of chronic pancreatitis?
  • What is the most common treatment for lymphoblastic lymphoma?
  • All disorders associated with ARDS cause massive pulmonary what?
  • Which term refers to a moving clot that blocks a vessel?
  • Which statement best describes the cause of galactorrhea?
  • During a thyroid storm, which assessment findings would the nurse most likely observe?
  • Which statement is true regarding stress ulcers after severe trauma?
  • Pain and inflammation associated with gout are caused by crystallization of which substance?
  • Polycythemia is best described as?
  • The nurse explains that myocardial ischemia is usually reversible within about 20 minutes because:
  • Which dietary modification is commonly recommended for benign breast disease?
  • Which statement correctly describes osteoarthritis?
  • Lymphomas are a diverse group of neoplasms. Which two broad categories describe them?
  • Which category is associated with thrombotic thrombocytopenic purpura (TTP) findings?
  • Severe trauma can result in the release of which substance from skeletal muscle cells, causing a life-threatening condition called rhabdomyolysis?
  • Malabsorption of which vitamin due to ileal mucosa injury is common in Crohn's disease?
  • A set of pins connected to stabilizing bars on the outside of the patient is a type of treatment of fractures called
  • The main white blood cell that plays a role in the development of the fatty streak in atherosclerosis is the:
  • In ARDS, the lungs are primarily affected by which process?
  • Which laboratory test helps support a suspected pulmonary embolism but is not specific?
  • Which statement about phimosis is correct?
  • Which of the following is NOT listed as a finding associated with thrombotic thrombocytopenic purpura (TTP)?
  • Classification of anemias is based on changes in cell sizes and hemoglobin content, indicated by which suffixes?
  • What is the name for the condition that is the result of increased pressure within a muscle compartment, potentially causing local tissue hypoxia and necrosis?
  • Which of the following best describes the classic symptoms of a small bowel obstruction?
  • Which disease is characterized by clonal proliferation of plasma cells producing monoclonal immunoglobulins?
  • Visceral pain is often referred to which location?
  • One complication of sustained hypertension is:
  • Which assessment finding is typical for chronic bronchitis?
  • Benign ovarian cysts can be categorized as which of the following groupings?
  • Which statement correctly links gastrectomy to vitamin B12 deficiency?
  • An abnormal dilation of vein within the spermatic cord that can lead to infertility is known as a:
  • Balanitis is defined as which condition?
  • A patient has heparin-induced thrombocytopenia (HIT). Which condition is a priority to assess?
  • Which of the following is a risk factor for endometrial cancer?
  • In Zollinger-Ellison syndrome, gastrin-secreting tumors most commonly arise in which locations?
  • Visceral pain is defined as pain that originates in which tissue?
  • Cryptorchidism is best described as which?
  • A peptic ulcer is best described as which of the following?
  • A patient is diagnosed with chronic pulmonary disease and elevated pulmonary vascular resistance. Which of the following heart failures does the nurse assess for in this patient?
  • Which condition is defined by a productive cough for at least 3 months in two consecutive years?
  • A patient with hemoptysis, night sweats, and fatigue who is feverish is suspected of having which condition?
  • A patient's coronary blood flow is insufficient to meet the metabolic demands of the myocytes. Which term will the nurse use to describe the process?
  • Which suffix indicates changes in cell size?
  • Gastrectomy commonly leads to a deficiency of which vitamin due to decreased intrinsic factor production?
  • Newly diagnosed type 1 diabetes is most characteristically associated with which laboratory finding?
  • ARDS-related pulmonary involvement is characterized by which primary process?
  • Exposure in utero to non-steroidal estrogens (diethylstilbestrol [DES]) also has been identified as a risk factor for:
  • Neutrophilia with a left shift is most commonly associated with which condition?
  • In disseminated intravascular coagulation (DIC), which laboratory result is typically elevated?
  • Osteomyelitis is most commonly caused by which route of infection in adults?
  • Leukemia is classified into which two main categories?
  • Thrombocytopenia is defined as a platelet count below 150,000/µL. Which option states this threshold?
  • What is the medical term for the sensation of feeling short of breath?
  • Burkitt lymphoma is a highly aggressive cancer with three main types. Which type is associated with EBV and commonly found in Africa?
  • Which laboratory test should be ordered to help evaluate suspected DIC?
  • Which concept should the nurse include when describing the pathophysiology of thrombotic thrombocytopenic purpura?
  • Which statement best describes lymphoblastic lymphoma?
  • What is the first sign of lymphoblastic lymphoma?
  • Dermoid cysts are tumors that contain elements of skin, hair, glands, muscle, cartilage, and bone that can eventually develop into:
  • Which organism is most commonly responsible for urinary tract infections?
  • Which set of factors comprises the Virchow triad?
  • In glomerulonephritis, which mechanism represents a major component of both primary and secondary glomerular injury?
  • What is the common pathologic feature across all forms of leukemia?
  • Relief of bilateral kidney obstruction resulting in post-obstructive diuresis has associated risks?
  • Which statement best defines a hydrocele?
  • Which statement about acute pancreatitis is true?
  • What intervention is recommended for patients with benign breast disease?
  • In a patient with chronic lung disease and elevated pulmonary vascular resistance, which heart chamber is most stressed?
  • Endometriosis can cause infertility due to inflammatory reaction at sites outside the uterus. Which option best reflects this statement?
  • Endometrial polyps consist of which description?
  • Which symptom is commonly associated with Hodgkin's lymphoma and considered a B symptom?
  • Mitogens, such as angiotensin II, and growth factors stimulate:
  • In a patient with a stress ulcer after severe trauma, which would be included in the initial assessment?
  • Gynecomastia incidence is greatest among which groups?
  • Which disorder is most commonly associated with bright red blood in the stools?
  • If a patient's history indicates that the cardiac valve disease is autosomal dominant, which diagnosis will the nurse observe written in the chart?
  • Which of the following are common disorders of the scrotum?
  • Obstruction to pulmonary blood flow results in which of the following?
  • What is the most common cause of hypoparathyroidism?
  • Which type of cell is most affected by acute leukemia?
  • A platelet count of 9,000/mm3 predisposes a patient to which complication?
  • In glomerulonephritis, which mechanism is a major component of injury?
  • Adenomyosis is defined as which of the following?
  • Which statement best explains why myocardial ischemia can be reversed if blood flow is restored within a short window?
  • A patient has chronic pyelonephritis. What would the nurse expect to see in this patient?
  • The best treatment for multiple myeloma is which of the following?
  • Thrombocytopenia is defined as a platelet count below what value?
  • A patient has multiple myeloma. Which area in the body does the nurse closely monitor for tumor masses?
  • Polycystic ovarian syndrome results in stimulation of follicle growth without ovulation and generally leads to:
  • A patient with cystitis reports painful urination. The nurse will document this symptom as which of the following?
  • In the early development of atherosclerosis, which cell type is prominently involved in forming the fatty streak?
  • Burkitt lymphoma is one of three main types; which type is endemic and commonly found in Africa?
  • Which statement about intestinal obstruction is true?
  • Uncorrected cryptorchidism is associated with which of the following outcomes?
  • Constipation is defined as which of the following?
  • What term describes dyspnea that occurs when an individual lies flat, common in heart failure?
  • Which disease is characterized by malignant plasma cells in the bone marrow?
  • In AIDS, which laboratory parameter should be monitored to assess immune status?
  • The bladder dysfunction caused by neurologic disorders like stroke, traumatic brain injury, dementia, and brain tumors is called?
  • Which term best describes a fixed clot that blocks within a vessel?
  • Prinzmetal angina is caused by:
  • Which statement best describes the initiation of kidney stone formation?
  • Galactorrhea is characterized by which of the following?
  • In lymphoblastic lymphoma, which lymph node regions are commonly involved?
  • Which molecule is a mitogen that contributes to vascular smooth muscle proliferation?
  • A high ventilation-perfusion ratio can be caused by which of the following?
  • A 14-year-old girl has failed to menstruate and develop secondary sex characteristics. What term describes this condition?
  • A patient has lymphoblastic lymphoma. Which organ is most affected?
  • A factor that contributes to osteoporosis in postmenopausal women is which of the following?
  • A patient presents with a UTI. The most common causative pathogen is which of the following?
  • What term describes hypertrophy of the nailbeds due to chronic hypoxemia?
  • Which cancer is the nurse testing for when the Papanicolaou test (Pap smear) is used for routine screening?
  • Chronic pyelonephritis can lead to which long-term kidney change?
  • Gynecomastia is described as which statement?
  • In osteomyelitis, the infectious organism most commonly identified is which of the following?
  • Which laboratory parameter should be monitored closely in a patient with AIDS?
  • Which organism is commonly associated with peptic ulcers?
  • A fracture that has broken into several fragments is termed:
  • Secondary hypertension is caused by:
  • Which statement accurately describes the classic symptoms of small bowel obstruction?
  • In AIDS, which laboratory parameter should be monitored closely to assess immune status?
  • Tuberculosis is suggested by which combination of symptoms?
  • The pathophysiology of type 1 diabetes mellitus involves which of the following?
  • In utero exposure to diethylstilbestrol (DES) has been identified as a risk factor for which cancer?
  • To help confirm pulmonary embolus, which laboratory test should be checked?
  • A major cause of myxedema coma is which of the following?
  • Balanitis risk factors include which of the following?
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